"The ejection seat is designed to permit safe pilot ejection up to Mach 4.0 at any altitude of up to 120,000 feet. A ballistic-rocket type catapult supplies the necessary propulsion force to eject the seat and pilot from the airplane."
Excerpt from the X-15 flight manual. Yes, because launching yourself out of an airplane strapped to a mini rocket engine 22 miles above the earth while going 2,500 MPH is “safe”.